Saturday, January 1, 2022

Understanding X DNA

Understanding X DNA

This is a bare bones basic overview of X-DNA and why it is important.  I solve alot of mysteries.  My focus is on the immediate family of people who are adopted or they are missing one parent, usually a father.  Going back to high school biology, women are XX and men are XY.  

Edward's X-DNA Inheritance

Edward, an adoptee, can only inherit X-DNA from his mother.  She inherited it from her mother and father but as we get to the men in this lineage, they can only inherit their X from their mother.  The other half of Edward's 23rd chromosome is the Y-DNA that comes directly down the paternal lineage.  

XDNAMale.gif

How Does This Help? 

Using X DNA to narrow down Edward's birth family can be extremely helpful.  If a male tester matches with another male tester on the 23rd chromosome, we know that that the connection between the 2 researchers are on the maternal line of their family trees.  

In the example below, Edward, our adoptee, matches Jeff, another researcher, but at a very small amount. Because they match on the X DNA the match is on Jeff's maternal lineage as well as Edward's.  Building out Jeff's pedigree tree and identifying where his X DNA could have come from will help us find common matches with one of these surnames.  

Jeff
Shared DNA: 43 cM 
Chromosome Browser from 23 and ME Test Results  

Building out the pedigree chart for this match might yield some valuable surnames but the reality is that while we know these men match on Edward's maternal lineage, the exact match will likely be hard to identify as it is many generations back.  They only share 43 cM.  

This is still very important because Jeff shares several matches with Edward and we can safely assume that these are on his mother's side of the family tree.  

When we look at the matches that Jeff and Edward have in common, we may find some closer matches that are not X DNA matches and that is ok.  Unless there is a crossover between Edward's maternal and paternal lineage, we are still looking at his mother's side of the tree.  

This chromosome browser example is from Edward's test results with 23 and ME.  But to gain a broader number of maternal matches, we went to Edward's test results on ancestry.com and found that some of the matches that we have identified as maternal have also tested on ancestry.com.  Ancestry has a larger database of testers and some of them share much more autosomal DNA with Edward making it easier to narrow down this lineage.  As an added bonus, we found a half-sister to Edward using the gedmatch.com toolset.  

Jane's X-DNA Inheritance

On our 23rd chromosome, or as I call it, our gender chromosome, women inherit X DNA from their mother and their father.  Jane's mother inherits the X DNA from both her mother and her father.  But Jane's father can only inherit X DNA from his maternal lineage.  

I often look for X-DNA matches for women adoptees that are male. While "Jane" inherits X-DNA from both of her parents, her male match can only inherit his X DNA from his mother's lineage.  

In this case, our adoptee, Jane, has a pair of half nephews.  With the amount of DNA shared between Jane and John, it would appear that Jane and John could be either a 1st cousin or a half nephew, but a couple of additional clues help guide our research.  John matches another male and these men are much closer in age to each other than they are to Jane.  They are also half-brothers.  What we do know for sure is that the match runs up through John and his half-brother's mother's lineage.  We do not know yet if this is on Jane's maternal or paternal lineage.  

John 
Shared DNA: 839 cM 

Additional research has found that John's maternal grandfather was also adopted, and shared common ancestor is Jane's paternal grandmother which is John's great grandmother.  Jane's paternal grandfather is still a mystery.  

X-DNA is a very important tool in the search angel's toolbox and I highly recommend that adoptees test in multiple test locations starting with ancestry and 23andME.  






Friday, December 31, 2021

How Do I Determine the Connection?

Perhaps your results have just come in or maybe you just don't understand how to figure them out!  The fact is that DNA can be confusing but by breaking down the basics into bitesize pieces, it can help you better understand how you are connected to others.  

The testing companies offer up suggestions on how you might connect to another tester but I don't find a lot of accuracy in some of those predicted relationships and use the chart provided by ISOGG.org to help me determine the possible connections.  

Average Shared Autosomal DNA and Relationships 

NOTE: This is not my work, please credit the original source.


Source of table information: http://isogg.org/wiki/Autosomal_DNA_statistics



Thursday, December 30, 2021

Solve Your Mystery

Unknown Parentage

DNA tests are often taken by people who want to know more about their family lineage but what happens if your test does not match up with who you believe are your parents or if you are adopted. 

One of the best things that you can do to help solve your mystery of that of someone else, is to create a mirror tree.  In today's youtube video, I offer up suggestions on how to create that mirror tree.   

Build A Mirror Tree from DNA Matches - YouTube 

Wednesday, December 29, 2021

DNA Ethnicity Estimates

German, Irish or Swedish

Have you heard the story that you have royalty in your family linage?  Or perhaps you have Native American heritage in your blood.  But just how is that determined?  What does the DNA testing services provide in terms of your ethnic background?  

The testing companies are constantly refining their ethnicity estimates based on updated testing.  While I can trace a number of my ancestors to Switzerland and Germany, I seem to show up with more UK in my heritage.  It is important to understand the basics of recombination as well.  A good dose of history is another plus!  

In the end, this is a great "coffee shop" conversation topic.  

Check out this youtube video that I like to call, "How Irish Am I?"  Recombination and Ethnicity - YouTube

Tuesday, December 28, 2021

Grandparent Connections

How Many are There? 

Just how many grandparents or sets of grandparents do you have?  It depends on how far you can go back in time.  I find that when I am trying to solve a mystery, I need to group people together through the "shared matches" tools provided by the testing companies.  Looking at my results, I find that I often have a number of people who are in common with me and each other but how do I work through this? 

Find the Most Common Recent Ancestor

Finding the shared ancestor between the matches is a GREAT way to narrow down your search but just how many grandparents are there? 

Grandparents


Grouping people together in matched sets will also help you determine the correct connections. But just how many "grandparents" can you expect to find when building your mirror tree?


Cousin
Shared Grandparent
Possibilities
1st 
Grandparent
4
2nd
Great Grandparents
8
3rd
Great Great Grandparents
16
4th
Great Great Great Grandparents
32
5th
Great Great Great Great Grandparents 
64

 

Understanding Matches on the 23andMe Tool

23andMe Matching

I love the way 23 and Me provides a chromosome browser to help me understand how / where matches share DNA.  Ancestry.com does not offer this toolset.  

This is a clear difference between Ancestry.com and 23andME.  Don't get me wrong, Ancestry has many great features not offered in 23andMe.  MyHeritage and FTDNA have their unique tools that help solve mysteries as well.  

Check out my youtube video which may help you better understand matching on 23andMe.  Understanding Centimorgans and DNA Matches - YouTube 

Sunday, December 26, 2021

Autosomal DNA Basics

Finding Family Connections 

Autosomal DNA is one of the best tools we have to find "closer" genetic family matches.  As an example, if you are looking for your ancestor who you believe arrived with the Mayflower, this is not likely going to help you.  But if you are looking to determine a parent, sibling, grandparent and any number of various cousins, this is a great tool to use.  

Recombination

Autosomal DNA follows a somewhat predictable pattern and the fact is that while we inherit half of our DNA from our mother and half from our father, we do not necessarily inherit 25% from each grandparent.  

Check out my youtube video to help get a better understanding of recombination.  I call it the "jelly bean" recombination.  Jelly Bean Recombination Model - YouTube 

Understanding X DNA

Understanding X DNA This is a bare bones basic overview of X-DNA and why it is important.  I solve alot of mysteries.  My focus is on the im...